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Autologous platelet-rich fibrin to treat difficult nonhealing diabetic foot wounds with exposed bone – A case report of this safe, effective, and economical method
Riju Ramachandran Menon1, Anoop Vasudevan Pillai1, Veena Shenoy2, Sundeep Vijayaraghavan3
1 Department of General Surgery, Amrita School of Medicine, Amrita Institute of Medical Sciences, Amrita Viswavidyapeetham, Kochi, Kerala, India
2 Department of Transfusion Medicine, Amrita School of Medicine, Amrita Institute of Medical Sciences, Amrita Viswavidyapeetham, Kochi, Kerala, India
3 Department of Plastic Surgery, Amrita School of Medicine, Amrita Institute of Medical Sciences, Amrita Viswavidyapeetham, Kochi, Kerala, India
Correspondence Address:
Dr. Riju Ramachandran Menon
AG-1, Sterling Sarovar, Kosseri Lane, Edapally, Kochi, Kerala
India
 Source of Support: None, Conflict of Interest: None  | 2 |
DOI: 10.4103/amjm.amjm_58_20
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Diabetic wounds, especially with exposed bones, are notorious to cause complications. Various drugs and substances have been tried by different researchers in their quest for early painless healing. We report our patient with peripheral vascular disease (PVD) and chronic nonhealing wound with exposed bone successfully treated with autologous platelet-rich fibrin (PRF). Our patient with a diabetic foot ulcer and PVD underwent an amputation of the great toe. His wound could not be closed, and there was exposed bone on the floor of the ulcer. Regular treatment may have caused nonhealing, osteomyelitis, and spreading gangrene. His PVD contraindicated a vascular flap cover. Hence, we tried the use of autologous PRF on the wound. The hospital stay was minimized, adjuvant procedures were not needed, and the wound healed well in 4 weeks. PRF is a very economical and safe adjuvant in the fight to treat difficult wounds.
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